J Clin Oncol ; Continued investigations of various treatments for atrophic vaginitis are necessary. Tamoxifen has been the most widely used SERM and continues to be prescribed for premenopausal women with estrogen receptor positive tumors [ 38 ]. Avoid use of fabric softeners. Blood clots can also cause a stroke.
The information below does not include all possible side effects, and not all patients who take tamoxifen will have these symptoms.
Atrophic Vaginitis in Breast Cancer Survivors: A Difficult Survivorship Issue
Less common, but important side effects can include: All forms of local estrogen therapies have shown similar rates of effectiveness, although they have varying levels of systemic absorption [ 7141822232425465455565758 ]. These drugs inhibit the activity of the enzyme aromatase that is utilized to convert androgens to estrogens [ 35 ]. Please talk to your healthcare provider if you feel that you are troubled by these symptoms. This medication is classified as an "anti-estrogen.